When a mysterious illness causes children in Phanom Nakha to develop snake-like scales, Dr. Benedict is called in to investigate. Assisting him is Asia, a skilled medical illustrator chosen to document the strange phenomenon. Their journey takes an unexpected turn when they meet Phumkhaobin — a spirited yet enigmatic man, and the younger brother of Asia's friend, Pheka.

As the research deepens, Asia finds herself entangled not only in a medical mystery but also in the ancient legend of a village that worships serpents — where science and myth begin to blur, and fate takes a serpentine path of its own.